Santo Remedio

Regional Mexican cooking with Casona & Cantina energy

Santo Remedio brings its lively, regional Mexican cooking to Marylebone, adding a two-part Casona & Cantina format that suits quick catch-ups and relaxed meals. The brand began in London in 2016 and opened the Marylebone site in late 2024 after years refining tacos, tostadas and plates inspired by Mexico City, Yucatán and Oaxaca. Guests can expect bright flavours, warm hosting and a menu that moves from snacks to sharing dishes without fuss. The kitchen nixtamalises corn for soft tortillas, pairs seafood with crisp acidity, and balances slow-cooked guisados with salsas that have depth rather than heat alone. Drinks lean into agave spirits, with a tight list of tequilas, mezcal and cocktails alongside alcohol-free options. Weekends bring brunch built for an unhurried pace, and the team explains dishes clearly so first-timers feel at ease. The room’s colour and rhythm fit Marylebone, with staff managing walk-ins and bookings so service stays smooth.

Listed by the MICHELIN Guide, trusted by London diners

Experience comes from co-founders Edson and Natalie’s long London run and a growing group that treats hospitality as carefully as flavour. Expertise shows in technique from nixtamal to slow roasts, plus a bar team that steers guests through agave styles with confidence. Trust is supported by a current MICHELIN Guide listing, clear reservation paths and steady third-party coverage that confirms the Marylebone opening. Authoritativeness comes from a loyal following across the city and a format that flexes for lunch, date nights and small celebrations. In practice this means tidy allergen guidance, pacing that keeps food landing hot and a room where conversation carries. The Cantina suits a seat at the bar with margaritas and botanas, while the Casona offers fuller plates and sharing mains. For anyone seeking modern Mexican restaurant cooking in a central neighbourhood, Santo Remedio delivers colour, comfort and a confident sense of place that reads as distinctly Marylebone