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Luxborough Street runs north to south between Marylebone Road and Paddington Street, passing through one of the quieter residential quarters of Marylebone. Postcoded W1U, it falls within the Howard de Walden Estate's territory and was formerly known as Northumberland Street, a name it held until the twentieth century when it was renamed.
The street's most substantial historical association is with the St Marylebone Workhouse, established on this site in 1775 to provide relief for the parish poor. By the nineteenth century the complex had expanded into a substantial institution offering infirmary care and later training programmes under the Poor Law system. In 1930, following transfer to London County Council oversight, it was redesignated the St Marylebone Institution, and by 1949 it had become Luxborough Lodge, functioning as a residential care facility. The site today is occupied by the University of Westminster on its western side, giving the street an academic presence alongside the mansion blocks that line its eastern frontage.
Thomas de Quincey, later author of Confessions of an English Opium-Eater, lodged at number 5 in 1806 to 1807, an early connection between the street and literary London. Marylebone High Street lies a short distance to the west, and Luxborough Street offers a relatively direct pedestrian route between the High Street's amenities and the green space of Paddington Street Gardens at its southern end.
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