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Queen Anne Street runs east-west through the heart of the Howard de Walden Estate, connecting Harley Street in the west with Welbeck Street and beyond, in the W1G postal area. The street takes its name from Queen Anne, on whose death in 1714 the Marylebone manor passed through inheritance to the Harley family, forerunners of the Howard de Walden landholding that still manages this approximately 92-acre estate today.
The street's most distinguished building is Chandos House at No. 2, a Grade I listed town house designed by Robert Adam and built between 1769 and 1771. It remains one of the finest intact Adam interiors in London, with bow-ended reception rooms, a grand staircase, and original stucco ceilings. The Howard de Walden Estate Office itself has occupied No. 23 since a purpose-built structure was erected there in 1882.
By the 1840s Queen Anne Street had become part of the wider Harley Street medical district. Distinguished physicians including Walter Hayle Walshe (No. 37, late 1840s to c.1887) and paediatrician Sir George Frederic Still (No. 28, 1920s-30s) practised here. The combination of Georgian terraces, an Adam masterpiece, and an enduring medical presence gives the street considerable architectural and professional coherence.
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